منابع مشابه
Copper(II) mediated anion dependent formation of Schiff base complexes.
A tetranuclear mixed ligand copper(II) complex of a pyrazole containing Schiff base and a hydroxyhexahydropyrimidylpyrazole and copper(II) and nickel(II) complexes of the Schiff base having N-donor atoms have been investigated. A 2 equiv amount of 5-methyl-3-formylpyrazole (MPA) and 2 equiv of 1,3-diamino-2-propanol (1,3-DAP) on reaction with 1 equiv of copper(II) nitrate produce an unusual tet...
متن کاملSchiff Base Adducts of Hemoglobin
Normal and sickle erythrocytes were exposed in vitro to millimolar concentrations of 31 different carbonyl compounds. Schiff base (imine) linkages were formed with amino groups of intracellular hemoglobin. Adducts were isolated by gel electrofocusing and could be dissociated by dialysis. Aromatic aldehydes proved more reactive than aliphatic aldehydes, and ketones were unreactive. The influence...
متن کاملMetal-mediated base pairing within the simplified nucleic acid GNA.
Hydroxypyridone and pyridopurine homo- and hetero-base pairs have been investigated in the context of duplex GNA (glycol nucleic acid). Phosphoramidites for automated GNA solid phase synthesis were synthesized economically in a few steps starting from commercially available enantiopure glycidol. Similar to their behavior in DNA, the hydroxypyridone and pyridopurine homo-base pairs display a met...
متن کاملMolecular electrostatic potentials of DNA base-base pairing and mispairing.
An understanding of why adenine (A) pairs with thymine (T) and cytosine (C) with guanine (G) in DNA is very useful in the design of sensors and other related devices. We report the use of dissociation energies, geometries and molecular electrostatic potentials (MEPs) to justify the canonical (AT and CG) Watson-Crick pairs. We also analyze all mismatches in both configurations-cis and trans-with...
متن کاملDeconvolving RNA Base Pairing Signals
The structure of an RNA sequence encodes information about its biological function. A sequence is typically predicted to fold to a single minimum free energy conformation. But, an increasing number of RNA molecules are now known to fold into multiple stable structures. Discrete optimization methods are commonly used to predict foldings, and adding experimental data as auxiliary information impr...
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ژورنال
عنوان ژورنال: Nucleic Acids Symposium Series
سال: 2005
ISSN: 1746-8272,0261-3166
DOI: 10.1093/nass/49.1.185